Antithrombotic Therapy on Antithrombin Resistance in a Mouse Model
Knock-in of FII R593L produced ATR model mice, which showed a strong thrombotic tendency. Evaluation of antithrombotic therapies showed that anticoagulants with anti-FIIa effects were highly effective.
Authors
- Shuichi Okamoto (ORCID: https://orcid.org/0000-0002-2751-4904)
- Akira Takagi (ORCID: https://orcid.org/0000-0003-3607-1209)
- Takeshi Kanematsu (ORCID: https://orcid.org/0000-0001-9688-7782)
- Masahito IKAWA
- Naruko Suzuki (ORCID: https://orcid.org/0000-0001-6722-6918)
- Ayako Isotani (ORCID: https://orcid.org/0000-0002-4720-2318)
- Tetsuhito Kojima (ORCID: https://orcid.org/0000-0002-1905-1065)
- Tadashi Matsushita (ORCID: https://orcid.org/0000-0002-3646-3125)
- Shogo Tamura (ORCID: https://orcid.org/0000-0002-4960-1400)
- Atsuo Suzuki (ORCID: https://orcid.org/0000-0002-7194-3183)
- Nobuaki Suzuki (ORCID: https://orcid.org/0000-0003-2250-7964)
- Hinako Notoh
- Sachiko Suzuki
- Hitoshi Kiyoi
- Fumihiko Hayakawa
- Sena Tokumaru
Institutions
- Suzuki (Japan) (JP)
- Health Sciences University of Hokkaido (JP)
- Sapporo University (JP)
- Hokkaido University (JP)
- Nagoya University Hospital (JP)
- Nagoya University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1161/atvbaha.125.324007
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00