The second-generation 3D-Printed localization grid for MRI-guided interventional procedures

Patient-specific three-dimensional (3D)-printed magnetic resonance imaging localization grids (MR-Grids) have demonstrated feasibility as an assistive tool for image-guided interventional procedures. However, a limitation of conventional designs arises when the target lesion lies in an imaging plane where the discrete grid markers are not visible. To address this challenge, we proposed a patient-specific MR-Grid incorporating a contrast-filled flexible tubing system arranged in a criss-cross pattern, ensuring visibility across all imaging slices. The proposed MR-Grid comprises two primary components: (1) a 3D-printed patient-specific scaffold designed to conform to individual anatomical contours, and (2) a contrast-filled flexible tubing system inserted into the grooves of the scaffold. The MR-Grid was tested in an interventional procedure using a biopsy phantom containing MRI-visible lesions to validate its utility. The grid facilitated precise needle insertion by identifying the optimal entry point under MR guidance, demonstrating its potential to improve accuracy and efficiency in image-guided interventions. • Patient-specific localization Grid for MRI-guided interventional procedures • Criss-cross pattern with contrast-filled tubing to ensure visibility in all planes • Interchangeable T1/T2 contrast for optimized MRI guidance • Minimized metallic artifacts via SENSE parameter optimization