Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults
The findings of his work indicate that tPBM influences intrinsic brain activity by reorganizing oscillatory patterns and shifting network engagement. The redistribution from default mode toward executive systems, along with the nesting of faster rhythms within slower temporal structures, reflects a capacity for large-scale functional rebalancing. The results highlight tPBM's potential as a precision neuromodulation tool for modulating executive and cognitive control systems.
Authors
- Joseph A. Maldjian (ORCID: https://orcid.org/0000-0002-6384-1072)
- Hanli Liu (ORCID: https://orcid.org/0000-0002-6370-0704)
- George Alexandrakis
- Subrat Bastola
- Tyrell Pruitt
- Elizabeth M. Davenport
Institutions
- The University of Texas at Arlington (US)
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fnhum.2025.1704482
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Mental Health