Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults

The findings of his work indicate that tPBM influences intrinsic brain activity by reorganizing oscillatory patterns and shifting network engagement. The redistribution from default mode toward executive systems, along with the nesting of faster rhythms within slower temporal structures, reflects a capacity for large-scale functional rebalancing. The results highlight tPBM's potential as a precision neuromodulation tool for modulating executive and cognitive control systems.

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Publication Details

Journal
Frontiers in Human Neuroscience
Published
2026-01-08
DOI
https://doi.org/10.3389/fnhum.2025.1704482
Primary Topic
Laser Applications in Dentistry and Medicine
Type
article
Field-Weighted Citation Impact
0.00

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article

Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults

Joseph A. Maldjian, Hanli Liu, George Alexandrakis, Subrat Bastola et al.
Frontiers in Human Neuroscience
Laser Applications in Dentistry and Medicine
article

Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults

Joseph A. Maldjian, Hanli Liu, George Alexandrakis, Subrat Bastola, Tyrell Pruitt, Elizabeth M. Davenport
article en

Abstract

The findings of his work indicate that tPBM influences intrinsic brain activity by reorganizing oscillatory patterns and shifting network engagement. The redistribution from default mode toward executive systems, along with the nesting of faster rhythms within slower temporal structures, reflects a capacity for large-scale functional rebalancing. The results highlight tPBM's potential as a precision neuromodulation tool for modulating executive and cognitive control systems.

Frontiers in Human NeuroscienceVol. 19
The University of Texas at Arlington (US), Southwestern Medical Center (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
National Institutes of Health, National Institute of Mental Health
Openalex Percentile: Top 96%
Laser Applications in Dentistry and Medicine
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