Resorcimoline Protects Against Myocardial Ischemia–Reperfusion Injury via Suppression of Oxidative Stress
RML exerts cardioprotective effects by scavenging ROS and mitigating downstream oxidative damage in both in vitro and in vivo models of myocardial I/R injury, suggesting promise as a therapeutic agent against reperfusion-induced myocardial injury.
Authors
- Kenshi Yoshimura (ORCID: https://orcid.org/0000-0001-7839-5493)
- Joscha Mulorz
- Mihoko Takahashi (ORCID: https://orcid.org/0000-0003-2780-8141)
- Taisuke Harada (ORCID: https://orcid.org/0000-0002-2805-3003)
- Akihiro Higuchi
- Shinji Miyamoto (ORCID: https://orcid.org/0000-0002-4972-0717)
- Takayuki Kawashima (ORCID: https://orcid.org/0000-0003-1631-8497)
- Renpei Nagashima (ORCID: https://orcid.org/0009-0000-0586-5116)
- K Ueno (ORCID: https://orcid.org/0009-0004-6908-4537)
- Osamu Tokumaru
- Kazuki Mori
- Haruto Nishida
Institutions
- Kanazawa University (JP)
- Oita University (JP)
- Düsseldorf University Hospital (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1253/circj.cj-25-0926
- Citations
- 1
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 36.00
Funders
- American Heart Association
- European Society of Cardiology
- Japan Society for the Promotion of Science