Revealing the clinical significance of PASAT rejection in multiple sclerosis: Insights from patient-reported and clinician-assessed outcomes
PASAT rejection at first assessment identifies a subgroup of older PwMS with higher disability, lower education, and more pronounced cognitive and functional impairments, suggesting that test refusal may serve as a clinically relevant marker of overall vulnerability in MS.
Authors
- Andrea Tacchino (ORCID: https://orcid.org/0000-0002-2263-7315)
- Erica Grange (ORCID: https://orcid.org/0000-0001-5114-9276)
- Jessica Podda (ORCID: https://orcid.org/0000-0002-9327-9148)
- Federica Di Antonio
- Ludovico Pedullà
- Giampaolo Brichett
Institutions
- University of Siena (IT)
- Multiple Sclerosis Foundation (US)
- Associazione Italiana Sclerosi Multipla (IT)
Publication Details
- Journal
- Multiple Sclerosis and Related Disorders
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1016/j.msard.2026.106984
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00