Molecular Actions of Cyclophosphamide (CPA) in the Ovaries of Rats with Mammary Neoplasia

The obtained results highlight the importance of mechanisms contributing to ovarian toxicity from cancer chemotherapy, paving the way for developing targeted strategies for ovarian protection. Further functional experiments are needed to identify substances that could effectively preserve the fertility of female cancer survivors.

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Publication Details

Journal
Cancer Management and Research
Published
2026-01-01
DOI
https://doi.org/10.2147/cmar.s557751
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular Actions of Cyclophosphamide (CPA) in the Ovaries of Rats with Mammary Neoplasia

Anna Nynca, Tomasz Molcan, Renata E. Ciereszko, Sylwia Świgońska et al.
Cancer Management and Research
Reproductive Biology and Fertility
article

Molecular Actions of Cyclophosphamide (CPA) in the Ovaries of Rats with Mammary Neoplasia

Anna Nynca, Tomasz Molcan, Renata E. Ciereszko, Sylwia Świgońska, Brian K. Petroff
article en

Abstract

The obtained results highlight the importance of mechanisms contributing to ovarian toxicity from cancer chemotherapy, paving the way for developing targeted strategies for ovarian protection. Further functional experiments are needed to identify substances that could effectively preserve the fertility of female cancer survivors.

Cancer Management and ResearchVol. Volume 18
InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL), University of Warmia and Mazury in Olsztyn (PL), Michigan State University (US), Polish Academy of Sciences (PL)
Good health and well-being
Openalex Percentile: Top 96%
Reproductive Biology and Fertility
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