Afferent Renal Nerves Drive Sympathoexcitation and Hypertensive Heart Failure

Afferent renal nerve input activates the sympathetic nervous system before left ventricular systolic dysfunction and contributes to hypertensive HF, with PVN vasopressin driving this sympathoexcitation.

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Publication Details

Journal
Hypertension
Published
2026-01-07
DOI
https://doi.org/10.1161/hypertensionaha.125.25247
Primary Topic
Renin-Angiotensin System Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Afferent Renal Nerves Drive Sympathoexcitation and Hypertensive Heart Failure

Soichiro Kashihara, Masaaki Nishihara, Ryohei Miyamoto, Ayano Hara et al.
Hypertension
Renin-Angiotensin System Studies
article

Afferent Renal Nerves Drive Sympathoexcitation and Hypertensive Heart Failure

Soichiro Kashihara, Masaaki Nishihara, Ryohei Miyamoto, Ayano Hara, Sho Matsumoto, Shota Ikeda, Daisuke Yoshida, Ryosuke Nakashima, K Shinohara, Hiroyuki Tsutsui, Toru Hashimoto, Shunsuke Katsuki, Shouji Matsushima, Kohtaro Abe, Yoshiyasu Ono, Hiroka Nakashima
article en

Abstract

Afferent renal nerve input activates the sympathetic nervous system before left ventricular systolic dysfunction and contributes to hypertensive HF, with PVN vasopressin driving this sympathoexcitation.

HypertensionVol. 83(3)
Kyushu University (JP), Fukuoka International University (JP), Kyushu University Hospital (JP), Matsumoto University (JP)
Good health and well-being
Openalex Percentile: Top 96%
Renin-Angiotensin System Studies
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