Foam Sclerotherapy Alleviates Dermatological Symptoms of Lipodermatosclerosis of the Lower Extremities

Introduction Chronic venous disease (CVD) is a prevalent vascular condition that manifests through varicose veins and a variety of clinical symptoms. Lipodermatosclerosis (LDS), a severe complication of CVD, is characterized by pain, skin fibrosis, and significant impairment of the quality of life. Despite its clinical relevance, limited evidence exists regarding the improvement of dermatological symptoms following foam sclerotherapy. This study aimed to assess the effectiveness of foam sclerotherapy in treating dermatological manifestations in LDS patients. Materials and Methods In this case series, 28 patients with LDS who underwent foam sclerotherapy were evaluated. Pre‐ and posttreatment assessments focused on pain, skin pigmentation, and inflammation to determine symptom improvements. The Venous Clinical Severity Score (VCSS) was used to assess overall severity, and pain scores were recorded 1 week after the procedure. Results Foam sclerotherapy resulted in significant improvements in both overall symptom severity and inflammation, as measured by the VCSS. Notably, foam sclerotherapy provided more rapid pain relief compared with conventional medical treatments, with significant reductions observed within 1 week of treatment. Conclusions Foam sclerotherapy is a safe, effective, and minimally invasive treatment option for LDS patients, offering rapid clinical relief, particularly valuable in the context of delayed diagnosis and management. This approach may provide an alternative for patients who cannot tolerate conventional therapies.