Characterization of individuals fulfilling clinical criteria for limbic‐predominant age‐related TDP43 encephalopathy (LATE) in a tertiary memory clinic
In a tertiary memory clinic population, the newly proposed clinical LATE criteria reveal clinical and atrophy trajectories that are distinct from AD, especially for Probable LATE and Possible LATE-AD. Differential clinical and biological disease trajectories highlight the relevance of the LATE classification for diagnostic and prognostic purposes.
Authors
- Floor Duits
- Diana I. Bocancea (ORCID: https://orcid.org/0000-0001-8303-8933)
- Roos M. Rikken (ORCID: https://orcid.org/0000-0002-1357-2572)
- Annemieke J.M. Rozemüller (ORCID: https://orcid.org/0000-0003-2528-4428)
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- Ilse Bader
- Sophie E Mastenbroek (ORCID: https://orcid.org/0009-0006-2759-9588)
- Emma M. Coomans (ORCID: https://orcid.org/0000-0002-4289-9101)
- M. Vermeiren
- Casper de Boer
- Suzie Kamps (ORCID: https://orcid.org/0009-0009-4264-3040)
- Alex J. Wesseling
- Laura Jonkman
- Colin Groot (ORCID: https://orcid.org/0000-0002-4384-0160)
- Yolande A.L. Pijnenburg (ORCID: https://orcid.org/0000-0003-2464-1905)
- Hannah de Bruin (ORCID: https://orcid.org/0000-0002-9011-1120)
- C Teunissen
- Maria Carrigan
- Calandri Ismael Luis
- Lotte A. de Koning
- Frederik Barkhof
- Bastiaan G J van Tol
- Elsmarieke van de Giessen
- Ye Xia
- Wiesje M. van der Flier
- Betty M. Tijms
- Sven J van der Lee
Institutions
- Lund University (SE)
- Karolinska Institutet (SE)
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (AR)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Ludwig-Maximilians-Universität München (DE)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104809
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00