OxyR contributes to the oxidative stress capacity and virulence of hypervirulent Klebsiella pneumoniae ATCC 43816

Together, these findings demonstrate that OxyR is a key regulator of oxidative stress defense, biofilm formation, and systemic virulence in hvKP, providing new insight into OxyR-mediated pathogenic mechanisms in <i>K. pneumoniae</i>.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-01-07
DOI
https://doi.org/10.3389/fcimb.2025.1661384
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00

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article

OxyR contributes to the oxidative stress capacity and virulence of hypervirulent Klebsiella pneumoniae ATCC 43816

Jiangbin Wu, Guoxin Xu, ruxia zhang, Long Chen et al.
Frontiers in Cellular and Infection Microbiology
Antibiotic Resistance in Bacteria
article

OxyR contributes to the oxidative stress capacity and virulence of hypervirulent Klebsiella pneumoniae ATCC 43816

Jiangbin Wu, Guoxin Xu, ruxia zhang, Long Chen, Xinping Zhu, Yu Zheng, Chao Ding, Wanqiu Zhu
article en

Abstract

Together, these findings demonstrate that OxyR is a key regulator of oxidative stress defense, biofilm formation, and systemic virulence in hvKP, providing new insight into OxyR-mediated pathogenic mechanisms in <i>K. pneumoniae</i>.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Soochow University (CN), Zhangjiagang First People's Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 95%
Antibiotic Resistance in Bacteria
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OxyR contributes to the oxidative stress capacity and virulence of hypervirulent Klebsiella pneumoniae ATCC 43816 — Jiangbin Wu, Guoxin Xu, et al. · Frontiers in Cellular and Infection Microbiology (2026) | TGRS Research Map | TGRS