Comparison of IO-IO and IO-TKI Treatment Outcomes in Metastatic Renal Cell Carcinoma: Influence of Metastatic Site Count

The number of metastatic organs affects the efficacy of IO-TKI but has no effect on the efficacy of IO-IO treatment. We recommend considering the number of metastatic organs as an additional prognostic factor to optimize treatment selection for patients with mRCC.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2026-01-03
DOI
https://doi.org/10.21873/cdp.10513
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Comparison of IO-IO and IO-TKI Treatment Outcomes in Metastatic Renal Cell Carcinoma: Influence of Metastatic Site Count

T. Habuchi, Yuki Takai, Hiroshi Kikuchi, Yoichi M. Ito et al.
Cancer Diagnosis & Prognosis
Renal cell carcinoma treatment
article

Comparison of IO-IO and IO-TKI Treatment Outcomes in Metastatic Renal Cell Carcinoma: Influence of Metastatic Site Count

T. Habuchi, Yuki Takai, Hiroshi Kikuchi, Yoichi M. Ito, Kazuyuki Numakura, N. Tsuchiya, Ryuji Matsumoto, Yuya Sekine, Takashige Abe, Nobuo Shinohara, Ojiro Tokairin, Sei Naito, Haruka Miyata, Takahiro Osawa
article en

Abstract

The number of metastatic organs affects the efficacy of IO-TKI but has no effect on the efficacy of IO-IO treatment. We recommend considering the number of metastatic organs as an additional prognostic factor to optimize treatment selection for patients with mRCC.

Cancer Diagnosis & PrognosisVol. 6(1)
Yamagata University (JP), Akita University (JP), Hokkaido University (JP), Hokkaido University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 96%
Renal cell carcinoma treatment
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