Longitudinal Kinetics of T Cells and <scp>NK</scp> Cells After Pediatric Liver Transplant
T cell function was not reduced by 6 months following liver transplant. This suggests that it might be safe to discontinue viral prophylaxis or initiate vaccinations sooner than previously suspected. Tregs functional marker expression was intact by 6 months post-transplant suggesting lower risk of rejection in this cohort. Tacrolimus level may not be a good indication for immunocompetence and T cell functional assays may be more predictive of susceptibility to infection.
Authors
- Hayley A. Gans (ORCID: https://orcid.org/0000-0001-9190-263X)
- Sruti Nadimpalli (ORCID: https://orcid.org/0000-0003-0614-1720)
- Ayelet Rosenthal (ORCID: https://orcid.org/0000-0002-1143-829X)
- David M. Vu (ORCID: https://orcid.org/0000-0002-0930-4524)
- Sangeeta Kowli (ORCID: https://orcid.org/0000-0003-0362-572X)
- Sharon Chen (ORCID: https://orcid.org/0000-0002-3705-258X)
- Holden Maecker
Institutions
- Lurie Children's Hospital (US)
- Institute of Infection and Immunity (CA)
- Stanford University (US)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1111/petr.70257
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stanford Maternal and Child Health Research Institute