Traditional Chinese Medicine Ameliorates Depression via the Gut-Brain Axis: A Review Focus on NLRP3/TLR4-Mediated Inflammatory Pathways and Gut Microbiota Modulation
TCM alleviates depression by integrating gut microbiota modulation, inflammatory suppression, and neuroprotection through the GBA. This review highlights TCM's potential as a safe, alternative therapy for depression and identifies directions for standardized, large-scale clinical validation.
Authors
- Cedric Xia
- Qinming Yu
- Jiaming Xie
- Longfei Che
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Heilongjiang University of Chinese Medicine (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- Neuropsychiatric Disease and Treatment
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/ndt.s579710
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00