Therapeutic potential of tetrahydroxylated bile acids in reducing liver injury: Insights from the <i> Zfyve19 <sup>−/−</sup> </i> mouse model
THBA effectively alleviated cholestatic liver injury and fibrosis, and may represent a potential agent for the medical management of such diseases.
Authors
- Jiayan feng
- Yue Yu (ORCID: https://orcid.org/0000-0003-1398-243X)
- Jianshe Wang (ORCID: https://orcid.org/0000-0003-3032-9379)
- Renxue Wang
- Huiyu She (ORCID: https://orcid.org/0000-0002-7634-7217)
- T Liu
- Yanan Zhang
- Victor Ling
- Li Wang
Institutions
- BC Cancer Agency (CA)
- National Center on Birth Defects and Developmental Disabilities (US)
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Pediatric Investigation
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1002/ped4.70036
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fudan University
- National Key Research and Development Program of China