Long-term outcome of acquired transthyretin amyloidosis

Acquired ATTR amyloidosis frequently develops in long-term DLT recipients. Although tafamidis stabilizes clinical manifestations in most patients, it may not completely prevent disease progression in some cases. Further long-term evaluation is needed to determine optimal treatment strategies, including siRNA therapy.

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Publication Details

Journal
Amyloid
Published
2026-01-06
DOI
https://doi.org/10.1080/13506129.2025.2611257
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
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Long-term outcome of acquired transthyretin amyloidosis

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Long-term outcome of acquired transthyretin amyloidosis

Masayoshi Tasaki, Yukio Ando, Mitsuharu Ueda, K Obayashi, Yohei Misumi, Shiori Yamakawa, Tomoaki Taguchi, Taro Yamashita, Toshiya Nomura
article en

Abstract

Acquired ATTR amyloidosis frequently develops in long-term DLT recipients. Although tafamidis stabilizes clinical manifestations in most patients, it may not completely prevent disease progression in some cases. Further long-term evaluation is needed to determine optimal treatment strategies, including siRNA therapy.

Amyloid
Morpho (United States) (US), National Sanyo Hospital (JP), Department of Physiological Sciences (RU), Kawamura Hospital (JP), Kumamoto University (JP)
Good health and well-being
Openalex Percentile: Top 95%
Amyloidosis: Diagnosis, Treatment, Outcomes
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