Transitioning to Shorter, Oral Antimicrobial Therapy for Pelvic Osteomyelitis in Patients Living With Spinal Cord Injury
An 8-year prospective cohort study of pelvic osteomyelitis in patients living with spinal cord injury shows that 4- to 6-week, post-debridement, quinolone-sparing oral antimicrobial regimens were effective within multidisciplinary care. Clinical cure (89% at 12 months) remained high with shorter durations. These real-world findings support stewardship and inform prescribing and future trials.
Authors
- D. Perera
- S Motaganahalli (ORCID: https://orcid.org/0000-0002-6739-0424)
- Jason A. Trubiano (ORCID: https://orcid.org/0000-0002-5111-6367)
- Gemma K. Reynolds (ORCID: https://orcid.org/0000-0002-9561-3592)
- S. Vogrin
- Richard Clements
- Andrew Nunn
- Ash Thomas
- Ben Clegg
- Estelle Petch
- Caroline McFarlane
Institutions
- The University of Melbourne (AU)
- Peter MacCallum Cancer Centre (AU)
- Peter Doherty Institute (AU)
- Austin Health (AU)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1093/ofid/ofaf805
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00