Non‐Bismuth Quadruple Concomitant Treatment for <i>Helicobacter pylori</i> Eradication: A Systematic Review and Meta‐Analysis

Concomitant therapy is a highly effective first-line option for H. pylori eradication, particularly in single clarithromycin- or nitroimidazole-resistant strains. However, its efficacy is reduced in dual-resistant cases, in which alternative regimens may be preferred. Overall, its efficacy is comparable to that of hybrid and bismuth quadruple therapy. Its tolerability is generally acceptable.