A Humoral Dilemma: Reassessing Monkeypox Virus Neutralizing Antibodies at More Than 2 Years From Mpox or Modified Vaccinia Ankara-Bavarian Nordic Vaccination
MPXV-specific NAbs waned at >2 years from previous infection or vaccination, often becoming undetectable. Higher NAb titers at six months (univariate) and prior smallpox vaccination (multivariate) were associated with NAb detection at >2 years, whilst previous Mpox was marginally associated.
Authors
- Nicola Clementi (ORCID: https://orcid.org/0000-0002-1822-9861)
- Silvia Nozza
- Angelo Roberto Raccagni (ORCID: https://orcid.org/0000-0001-7811-6255)
- Nicolò Capra (ORCID: https://orcid.org/0000-0003-1974-2015)
- Elena Criscuolo (ORCID: https://orcid.org/0000-0003-0185-3147)
- Alberto Castagna (ORCID: https://orcid.org/0000-0001-9136-2055)
- Nicolò Moschetta
- Diana Canetti
- Gabriele Loi
- Riccardo Lolatto
Institutions
- Vita-Salute San Raffaele University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1093/infdis/jiag009
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 0.00