miR-146b-5p promotes prostate cancer progression by targeting and negatively regulating FOXO3 and its mechanism

miR-146b-5p drives PCa progression through the targeted downregulation of FOXO3, implicating it as a promising prognostic marker and therapeutic target.

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Publication Details

Journal
World Journal of Surgical Oncology
Published
2026-01-06
DOI
https://doi.org/10.1186/s12957-025-04161-x
Primary Topic
FOXO transcription factor regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

miR-146b-5p promotes prostate cancer progression by targeting and negatively regulating FOXO3 and its mechanism

Feng Feng, Meini Cen, Yin Yu, Zhao Wang et al.
World Journal of Surgical Oncology
FOXO transcription factor regulation
article

miR-146b-5p promotes prostate cancer progression by targeting and negatively regulating FOXO3 and its mechanism

Feng Feng, Meini Cen, Yin Yu, Zhao Wang, Baoji Xing
article en

Abstract

miR-146b-5p drives PCa progression through the targeted downregulation of FOXO3, implicating it as a promising prognostic marker and therapeutic target.

World Journal of Surgical OncologyVol. 24(1)
Hebei Medical University (CN), Harbin Medical University (CN), Third Affiliated Hospital of Harbin Medical University (CN), Shanxi Province Hospital of Traditional Chinese Medicine (CN), Shandong Provincial Hospital (CN), Affiliated Hospital of Youjiang Medical University for Nationalities (CN), Baise University (CN), First Affiliated Hospital of Hebei Medical University (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 95%
FOXO transcription factor regulation
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miR-146b-5p promotes prostate cancer progression by targeting and negatively regulating FOXO3 and its mechanism — Feng Feng, Meini Cen, et al. · World Journal of Surgical Oncology (2026) | TGRS Research Map | TGRS