Risk factors for periprosthetic joint infection following primary total knee arthroplasty: a systematic review and meta-analysis
The meta-analysis confirmed that longer operative time, obesity, male gender, diabetes, longer hospital stay, use of immunosuppressants, hypoalbuminemia, and underlying systemic inflammatory disease are risk factors for PJI after primary TKA. This systematic review and meta-analysis provide Level II evidence (according to the Oxford Centre for Evidence-Based Medicine criteria) for the identified risk factors.
Authors
- Maihemuti Yakufu (ORCID: https://orcid.org/0000-0001-9853-1923)
- Qingxue Zhu
- D. F. Li
- Abuduwupuer Haibier (ORCID: https://orcid.org/0000-0001-7420-9761)
- Ainikaer Abulaiti (ORCID: https://orcid.org/0009-0002-5661-5701)
- Heng Zhang
- Zhen Liu
- Zheng Wang
- Shuo Hao
- Jiashun Li
Institutions
- Xinjiang Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Sixth Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fsurg.2025.1715571
- Primary Topic
- Total Knee Arthroplasty Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Xinjiang Medical University
- Natural Science Foundation of Xinjiang