Nonlinear compartmental modeling of COVID-19 with dual dose vaccination using Mason graphs and variational iteration method

In this research work, a novel non-linear mathematical model has been proposed considering susceptible, quarantined, infected, recovered, and removed compartments before and after the 1st dose and 2nd dose of vaccination. For this dynamics model, the novel coronavirus COVID-19, a contagious disease, is taken as a case study in which its transmission, impact of vaccination, and mitigation have been discussed. This model may be helpful in numerous fields of epidemiology and dynamical systems; moreover, Mason Graph has been used to describe the mathematical model. The stability analysis and disease-free equilibrium points have been deliberated for the model. In this work, the semi-analytical technique Variational Iteration Method has been employed, which will assist researchers in the future by showing that if the rate of immunized personnel rises, then the infection rate decreases. It has been observed that the non-vaccinated personnel decrease with the passage of time due to the awareness campaign programs of the governments. Furthermore, it was observed that the removed rate also decreases with the passage of time as the immunized personnel rises. Mathematical software MAPLE has been used to calculate the analytical solutions of the aforementioned mathematical model.

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Publication Details

Journal
Scientific Reports
Published
2026-01-06
DOI
https://doi.org/10.1038/s41598-025-34692-y
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Nonlinear compartmental modeling of COVID-19 with dual dose vaccination using Mason graphs and variational iteration method

Shahid Mahmood, Aymen Flah, Ivo Pergl, Bilal Ahmad et al.
Scientific Reports
COVID-19 epidemiological studies
article

Nonlinear compartmental modeling of COVID-19 with dual dose vaccination using Mason graphs and variational iteration method

Shahid Mahmood, Aymen Flah, Ivo Pergl, Bilal Ahmad, Mohammad Ghatasheh, Umer Ghani
article en

Abstract

In this research work, a novel non-linear mathematical model has been proposed considering susceptible, quarantined, infected, recovered, and removed compartments before and after the 1st dose and 2nd dose of vaccination. For this dynamics model, the novel coronavirus COVID-19, a contagious disease, is taken as a case study in which its transmission, impact of vaccination, and mitigation have been discussed. This model may be helpful in numerous fields of epidemiology and dynamical systems; moreover, Mason Graph has been used to describe the mathematical model. The stability analysis and disease-free equilibrium points have been deliberated for the model. In this work, the semi-analytical technique Variational Iteration Method has been employed, which will assist researchers in the future by showing that if the rate of immunized personnel rises, then the infection rate decreases. It has been observed that the non-vaccinated personnel decrease with the passage of time due to the awareness campaign programs of the governments. Furthermore, it was observed that the removed rate also decreases with the passage of time as the immunized personnel rises. Mathematical software MAPLE has been used to calculate the analytical solutions of the aforementioned mathematical model.

Scientific ReportsVol. 16(1)
VSB - Technical University of Ostrava (CZ), Applied Science Private University (JO), University of Wah (PK), Government of Pakistan (PK), University of Business and Technology (SA), Middle East University (JO)
European Commission
Good health and well-being
Openalex Percentile: Top 95%
COVID-19 epidemiological studies
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