Asymmetric Michael–Mannich cascade reaction of azomethine ylides with isatin-derived trifluoromethyl acrylates catalyzed by a Cu( <scp>i</scp> ) catalyst

An efficient, reliable and atom-economic strategy employing azomethine ylides with isatin-derived trifluoromethyl acrylates has been developed to afford spirooxindole-pyrrolidine products featuring vicinal quaternary carbon centers.

Authors

Pingde Tao
Shengwen Yang (ORCID: https://orcid.org/0000-0001-9449-3077)
Saisai Yu
Shi-Wu Li
Xiaoying Cao

Institutions

Shihezi University (CN)

Publication Details

Journal: Organic Chemistry Frontiers
Published: 2026-01-01
DOI: https://doi.org/10.1039/d5qo01423a
Primary Topic: Fluorine in Organic Chemistry
Type: article
Field-Weighted Citation Impact: 0.00

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article

Asymmetric Michael–Mannich cascade reaction of azomethine ylides with isatin-derived trifluoromethyl acrylates catalyzed by a Cu( i ) catalyst

Pingde Tao, Shengwen Yang, Saisai Yu, Shi-Wu Li et al.

Jan 1, 2026

Organic Chemistry Frontiers

Fluorine in Organic Chemistry

article

Asymmetric Michael–Mannich cascade reaction of azomethine ylides with isatin-derived trifluoromethyl acrylates catalyzed by a Cu( i ) catalyst

Pingde Tao, Shengwen Yang, Saisai Yu, Shi-Wu Li, Xiaoying Cao

January 1, 2026article en

Abstract

Organic Chemistry FrontiersVol. 13(6)

Shihezi University (CN)

Openalex Percentile: Top 95%

Fluorine in Organic Chemistry

DOI Source OpenAlex

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Asymmetric Michael–Mannich cascade reaction of azomethine ylides with isatin-derived trifluoromethyl acrylates catalyzed by a Cu( <scp>i</scp> ) catalyst — Pingde Tao, Shengwen Yang, et al. · Organic Chemistry Frontiers (2026) | TGRS Research Map | TGRS