Association between vancomycin therapeutic drug monitoring and improved clinical outcomes in critically ill patients receiving renal replacement therapy: a retrospective cohort study
Vancomycin TDM was significantly associated with reduced 30-day mortality in critically ill patients receiving RRT, with an even stronger effect observed in those undergoing CRRT. These findings support the potential clinical relevance of TDM in this high-risk population.
Authors
- X W Tang
- Tingting Xie
- Huaidong Peng (ORCID: https://orcid.org/0000-0003-1817-516X)
- Dan Xu
- Lijin Chen
- Jinliang Cai
- Qilin Yang
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First People's Hospital of Foshan (CN)
- Foshan Second People's Hospital (CN)
- Guangdong 999 Brain Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/fphar.2025.1715023
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00