Immunogenicity of subunit vaccine of E2 protein against atypical porcine pestivirus in pigs
The results demonstrate that the Escherichia coli-expressed E2 protein elicits an immune response in pigs. The E2 subunit vaccine is a potential candidate for preventing APPV infection, and ISA 201VG and Gel 02 adjuvants are suitable candidate adjuvants for vaccine preparation. This study provides a foundation for further APPV vaccine research.
Authors
- Lu Guo (ORCID: https://orcid.org/0000-0003-4907-9912)
- Lu Yin (ORCID: https://orcid.org/0000-0002-1138-3225)
- Yongda Zhao
- Peixun Yuan
- Ling Chen
- Yufeng Huang
Institutions
- Qingdao Agricultural University (CN)
- Feed Control (Norway) (NO)
- Shandong Institute for Product Quality Inspection (CN)
- Qingdao Center of Resource Chemistry and New Materials (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fcimb.2025.1740259
- Primary Topic
- Animal Disease Management and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Qingdao Agricultural University