Lysophosphatidic acid: a promising biomarker for diagnosing sepsis and predicting in-hospital mortality
Reduced plasma LPA levels in sepsis patients are inversely correlated with infection/inflammation markers and SOFA scores. Together, these results suggest that LPA may serve as a potential diagnostic and prognostic biomarker for sepsis, supporting its potential as a complementary tool to enhance early risk stratification and guide bedside clinical decision-making.
Authors
- Pengfei Xuan
- Jingping Yang (ORCID: https://orcid.org/0009-0004-6463-3947)
- X. J. Li
- Hongyan Wang (ORCID: https://orcid.org/0000-0003-2710-8698)
- Tiewei Li
Institutions
- Zhengzhou Children's Hospital (CN)
- Baogang Group (China) (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1725394
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Inner Mongolia Medical University
- National Natural Science Foundation of China