Role of Reward Dysregulation in the Association Between Depression and Obesity: A Systematical Review
This review highlights that the comorbidity of obesity and depression can be explained through complex behavioral and neural mechanisms, particularly those involving reward processing pathways. Further longitudinal and intervention studies are warranted to clarify causal relationships and underlying mechanisms.
Authors
- Bing Cao (ORCID: https://orcid.org/0000-0001-5963-2676)
- Lin Han (ORCID: https://orcid.org/0000-0001-8730-2674)
- Yefei Xiao
- Roger S. McIntyre (ORCID: https://orcid.org/0000-0003-4733-2523)
- Xiao Gao (ORCID: https://orcid.org/0000-0003-4042-8362)
- Kayla M. Teopiz
- Xuan Zhang
Institutions
- Southwest University (CN)
- University of Toronto (CA)
- Xi'an Medical University (CN)
- Brain and Cognition Discovery Foundation (CA)
Publication Details
- Journal
- Obesity Reviews
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1111/obr.70082
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China