Implementation of guideline-recommended organ-protective therapy in people with type 2 diabetes and cardiovascular disease, heart failure, or kidney disease: real-world evidence from a German University Hospital

Guideline recommendations for organ protection in PwT2D and cardiorenal comorbidities are increasingly reflected in clinical practice, yet a substantial care gap persists, with the majority of individuals remaining untreated. Certain subpopulations - particularly women - are underrepresented among those receiving guideline adherent therapy. Further research into the causes of undertreatment and development of targeted implementation strategies is needed to close remaining evidence-practice gaps.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-06
DOI
https://doi.org/10.3389/fendo.2025.1736984
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
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article

Implementation of guideline-recommended organ-protective therapy in people with type 2 diabetes and cardiovascular disease, heart failure, or kidney disease: real-world evidence from a German University Hospital

Jens Kleesiek, Jasmin Klose, Young Hee Lee-Barkey, Julius Keyl et al.
Frontiers in Endocrinology
Diabetes Treatment and Management
article

Implementation of guideline-recommended organ-protective therapy in people with type 2 diabetes and cardiovascular disease, heart failure, or kidney disease: real-world evidence from a German University Hospital

Jens Kleesiek, Jasmin Klose, Young Hee Lee-Barkey, Julius Keyl, Alexander Brehmer, Susanne Reger-Tan, Tim Lenfers, Karzan Suliman, Bernd Stratmann
article en

Abstract

Guideline recommendations for organ protection in PwT2D and cardiorenal comorbidities are increasingly reflected in clinical practice, yet a substantial care gap persists, with the majority of individuals remaining untreated. Certain subpopulations - particularly women - are underrepresented among those receiving guideline adherent therapy. Further research into the causes of undertreatment and development of targeted implementation strategies is needed to close remaining evidence-practice gaps.

Frontiers in EndocrinologyVol. 16
University Hospitals of the Ruhr-University of Bochum (DE), Heart and Diabetes Center North Rhine-Westphalia (DE), Essen University Hospital (DE), Artificial Intelligence in Medicine (Canada) (CA)
Good health and well-being
Openalex Percentile: Top 95%
Diabetes Treatment and Management
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