Implementation of guideline-recommended organ-protective therapy in people with type 2 diabetes and cardiovascular disease, heart failure, or kidney disease: real-world evidence from a German University Hospital
Guideline recommendations for organ protection in PwT2D and cardiorenal comorbidities are increasingly reflected in clinical practice, yet a substantial care gap persists, with the majority of individuals remaining untreated. Certain subpopulations - particularly women - are underrepresented among those receiving guideline adherent therapy. Further research into the causes of undertreatment and development of targeted implementation strategies is needed to close remaining evidence-practice gaps.
Authors
- Jens Kleesiek (ORCID: https://orcid.org/0000-0001-8686-0682)
- Jasmin Klose (ORCID: https://orcid.org/0000-0002-1061-4386)
- Young Hee Lee-Barkey
- Julius Keyl (ORCID: https://orcid.org/0000-0002-5617-091X)
- Alexander Brehmer (ORCID: https://orcid.org/0009-0000-2795-6174)
- Susanne Reger-Tan
- Tim Lenfers
- Karzan Suliman
- Bernd Stratmann
Institutions
- University Hospitals of the Ruhr-University of Bochum (DE)
- Heart and Diabetes Center North Rhine-Westphalia (DE)
- Essen University Hospital (DE)
- Artificial Intelligence in Medicine (Canada) (CA)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fendo.2025.1736984
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00