Adjusting for truncated study duration in recurrent event analysis: A weighting approach for clinical trials

Unaccounted truncated follow-up in recurrent event studies can bias the risk estimation if unaccounted for. Our findings demonstrate that total time-based weighting effectively addresses this bias and enhances precision in both simulated and real datasets.

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Publication Details

Journal
PLoS ONE
Published
2026-01-07
DOI
https://doi.org/10.1371/journal.pone.0339887
Primary Topic
Pregnancy and preeclampsia studies
Type
article
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0.00
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article

Adjusting for truncated study duration in recurrent event analysis: A weighting approach for clinical trials

John Michael Raj A, Pratibha Dwarkanath, Tinku Thomas
PLoS ONE
Pregnancy and preeclampsia studies
article

Adjusting for truncated study duration in recurrent event analysis: A weighting approach for clinical trials

John Michael Raj A, Pratibha Dwarkanath, Tinku Thomas
article en

Abstract

Unaccounted truncated follow-up in recurrent event studies can bias the risk estimation if unaccounted for. Our findings demonstrate that total time-based weighting effectively addresses this bias and enhances precision in both simulated and real datasets.

PLoS ONEVol. 21(1)
Manipal Academy of Higher Education (IN), St. John's National Academy of Health Sciences (IN), St.John's Medical College Hospital (IN)
Openalex Percentile: Top 96%
Pregnancy and preeclampsia studies
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Adjusting for truncated study duration in recurrent event analysis: A weighting approach for clinical trials — John Michael Raj A, Pratibha Dwarkanath, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS