Economic costs at age five for very preterm children with congenital anomalies: evidence from a European cohort
Very preterm birth combined with the presence of a congenital anomaly is associated with increased health and social service costs and increased societal costs during the fifth year of life. Additional severe neonatal morbidity is independently associated with increased costs in this population. Very preterm birth together with a congenital anomaly creates substantial economic burdens for health and social care systems and families five years after birth.
Authors
- Marina Cuttini (ORCID: https://orcid.org/0000-0002-3284-6874)
- S Petrou
- Mairi Männamaa (ORCID: https://orcid.org/0000-0001-5234-6474)
- Anna‐Veera Seppänen (ORCID: https://orcid.org/0000-0001-5615-0639)
- Rolf F. Maier (ORCID: https://orcid.org/0009-0005-0032-3859)
- Olaf Gefeller (ORCID: https://orcid.org/0000-0002-8985-7582)
- Patrick Truffert (ORCID: https://orcid.org/0000-0001-9631-4669)
- Jennifer Zeitlin (ORCID: https://orcid.org/0000-0002-9568-2969)
- Veronica Siljehav (ORCID: https://orcid.org/0009-0004-7763-7760)
- Lazaros Andronis (ORCID: https://orcid.org/0000-0001-7998-7431)
- S. W. Kim
- Corine Koopman-Esseboom
- Heili Varendi
- A. Burguet (ORCID: https://orcid.org/0000-0001-5140-2884)
- Carina Rodrigues (ORCID: https://orcid.org/0000-0003-1720-2808)
- L. Wohlers
- Pernille Pedersen (ORCID: https://orcid.org/0000-0002-0854-1018)
- Patrick J. Van Reempts
- Italy M. Cuttini
- Poland
- Portugal H. Barros
- S. W. Kim
- R. El Rafei
- P. H. Jarreau
- P. Y. Ancel
- I. Sarrechia
- Germany
- R. F. Maier
- V. Carnielli
- E. Ortibus
- Elizabeth Draper
- C. Bonnet
- A. Oostra
- Sweden
- Estonia
- B. Misselwitz
- EFCNI
- A. Montgomery
- E. S. Draper
- Belgium
- S. Mader
- S. J. Johnson
- Denmark
- France
- A. M. Aubert
Institutions
- Poznan University of Medical Sciences (PL)
- University of Modena and Reggio Emilia (IT)
- Marche Polytechnic University (IT)
- University of Antwerp (BE)
- University of Leicester (GB)
- Inserm (FR)
- Philipps University of Marburg (DE)
- Universidade do Porto (PT)
- Université Paris Cité (FR)
- Ghent University Hospital (BE)
- Hvidovre Hospital (DK)
- Tartu University Hospital (EE)
- Copenhagen University Hospital (DK)
- Karolinska Institutet (SE)
- University of Warwick (GB)
- University of Oxford (GB)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Sorbonne Paris Cité (FR)
- IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
- Assistance Publique – Hôpitaux de Paris (FR)
- Maternité Port Royal (FR)
- Hôpital Jeanne de Flandre (FR)
- CHU Dijon Bourgogne (FR)
- Bambino Gesù Children's Hospital (IT)
- Universitair Ziekenhuis Brussel (BE)
- Maison des Sciences sociales et des Humanités de Dijon (FR)
- Ziekenhuis Oost-Limburg (BE)
- IRCCS Eugenio Medea (IT)
- Ospedale degli Infermi (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Hôpital Intercommunal de Créteil (FR)
- Wilhelmina Children's Hospital (NL)
- Centre de Recherche Épidémiologie et Statistique (FR)
- University of Tartu (EE)
- Newcastle University (GB)
- KU Leuven (BE)
Publication Details
- Journal
- Pediatric Research
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1038/s41390-025-04672-z
- Primary Topic
- Infant Development and Preterm Care
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- European Commission
- Oxford Health NHS Foundation Trust
- National Institute for Health and Care Research Applied Research Collaboration Oxford and Thames Valley