β-sitosterol ameliorates myocardial infarction injury via modulating the NF-κB and necroptosis signaling pathways
β-SITO demonstrates significant therapeutic potential for improving post-MI recovery. Its cardioprotective effects are likely mediated through the modulation of NF-κB and necroptosis signaling pathways, highlighting it as a promising candidate for MI treatment.
Authors
- Shu-Yan Fan Jiang
- Z Shan
- Jun-Xin Lin
- Jia-jia Xu
- Min-Wei Chen
- Di Xiao (ORCID: https://orcid.org/0009-0007-4725-4752)
- Long-zhen Lai
- Zheng-hao Zhang
Institutions
- First Affiliated Hospital of Xiamen University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fphar.2025.1719074
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Xinjiang