The Risk of Hypothyroidism With the Use of <scp>GLP</scp> ‐1 Receptor Agonists in Saudi Arabia

In this real-world analysis, GLP-1RA use was not associated with an increased incidence of hypothyroidism compared to DPP-4is. Findings were consistent across sensitivity and subgroup analyses. Although findings do not suggest a short-term risk, longer-term studies are warranted to further evaluate thyroid safety.

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Publication Details

Journal
Pharmacoepidemiology and Drug Safety
Published
2026-01-01
DOI
https://doi.org/10.1002/pds.70315
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The Risk of Hypothyroidism With the Use of GLP ‐1 Receptor Agonists in Saudi Arabia

Yasser Albogami, Raseel Alroba, Adel Alrwisan, Omar A. Alshaya et al.
Pharmacoepidemiology and Drug Safety
Thyroid Disorders and Treatments
article

The Risk of Hypothyroidism With the Use of GLP ‐1 Receptor Agonists in Saudi Arabia

Yasser Albogami, Raseel Alroba, Adel Alrwisan, Omar A. Alshaya, Ohoud Almadani, Almaha Alfakhri
article en

Abstract

In this real-world analysis, GLP-1RA use was not associated with an increased incidence of hypothyroidism compared to DPP-4is. Findings were consistent across sensitivity and subgroup analyses. Although findings do not suggest a short-term risk, longer-term studies are warranted to further evaluate thyroid safety.

Pharmacoepidemiology and Drug SafetyVol. 35(1)
King Saud University (SA), Saudi Arabian Monetary Authority (SA), National Guard Health Affairs (SA)
Openalex Percentile: Top 95%
Thyroid Disorders and Treatments
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