Integrated spatial and single-cell transcriptomics reveals RPL8 as a prognostic biomarker and therapeutic target in hepatocellular carcinoma

RPL8 drives HCC progression and immune evasion, qualifying it as a diagnostic biomarker and therapeutic target.

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Publication Details

Journal
Translational Oncology
Published
2026-01-06
DOI
https://doi.org/10.1016/j.tranon.2025.102663
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated spatial and single-cell transcriptomics reveals RPL8 as a prognostic biomarker and therapeutic target in hepatocellular carcinoma

Hui Yin, Jinna Michelle Tan, Fu Long, Jiaqian He et al.
Translational Oncology
Ferroptosis and cancer prognosis
article

Integrated spatial and single-cell transcriptomics reveals RPL8 as a prognostic biomarker and therapeutic target in hepatocellular carcinoma

Hui Yin, Jinna Michelle Tan, Fu Long, Jiaqian He, Hongsheng Lin, Yuzhen Luo, Mingfen Li, Hemeng Wu, Yaoyang Li, Junzhu Liang
article en

Abstract

RPL8 drives HCC progression and immune evasion, qualifying it as a diagnostic biomarker and therapeutic target.

Translational OncologyVol. 64
Guangxi University (CN), The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN), Guangxi University of Chinese Medicine (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 96%
Ferroptosis and cancer prognosis
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