Sjögren’s disease metabolome reveals biomarker signatures to characterise patients and assess disease activity

A plasma metabolome biomarker signature was developed that can be implemented in clinical studies by simple blood collection. The biomarker signature allows to characterise disease activity of patients with SjD at baseline and provides a basis for future studies to investigate its potential utility in monitoring therapeutic intervention.

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Publication Details

Journal
RMD Open
Published
2026-01-01
DOI
https://doi.org/10.1136/rmdopen-2025-006312
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

Sjögren’s disease metabolome reveals biomarker signatures to characterise patients and assess disease activity

Madeleine Suffiotti, André van Maurik, Daniel S. Strasser, Łukasz Kozera et al.
RMD Open
Salivary Gland Disorders and Functions
article

Sjögren’s disease metabolome reveals biomarker signatures to characterise patients and assess disease activity

Madeleine Suffiotti, André van Maurik, Daniel S. Strasser, Łukasz Kozera, Lukas B. Tanner, Agata Sebastian
article en

Abstract

A plasma metabolome biomarker signature was developed that can be implemented in clinical studies by simple blood collection. The biomarker signature allows to characterise disease activity of patients with SjD at baseline and provides a basis for future studies to investigate its potential utility in monitoring therapeutic intervention.

RMD OpenVol. 12(1)
GlaxoSmithKline (United Kingdom) (GB), Age UK (GB), Wroclaw Medical University (PL), Idorsia (Switzerland) (CH), Łukasiewicz Research Network – PORT Polish Center for Technology Development (PL)
Good health and well-being
Openalex Percentile: Top 96%
Salivary Gland Disorders and Functions
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