Polymorphisms in CLOCK and ARNTL/BMAL-1 genes in multiple sclerosis: a systematic review and meta-analysis

Based on the limited available evidence, there may be an ethnic-specific association between ARNTL/BMAL-1 and CLOCK gene and MS susceptibility; however, considering the limitations such as the small number of included studies and small sample sizes, future multiethnic studies are needed on this topic.

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Publication Details

Journal
European journal of medical research
Published
2026-01-06
DOI
https://doi.org/10.1186/s40001-025-03798-4
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

Polymorphisms in CLOCK and ARNTL/BMAL-1 genes in multiple sclerosis: a systematic review and meta-analysis

Amirreza Naseri, Mobina Oladghaffari, Sina Hamzehzadeh, Fatemeh Malekinejad et al.
European journal of medical research
Multiple Sclerosis Research Studies
article

Polymorphisms in CLOCK and ARNTL/BMAL-1 genes in multiple sclerosis: a systematic review and meta-analysis

Amirreza Naseri, Mobina Oladghaffari, Sina Hamzehzadeh, Fatemeh Malekinejad, Narges Koohi, Seyedehyasmin Moghaddamziabari, Heliya Bandehagh, Hanieh Salehi-Pourmehr, Shahrzad Fakhkhari, Mahnaz Talebi
article en

Abstract

Based on the limited available evidence, there may be an ethnic-specific association between ARNTL/BMAL-1 and CLOCK gene and MS susceptibility; however, considering the limitations such as the small number of included studies and small sample sizes, future multiethnic studies are needed on this topic.

European journal of medical researchVol. 31(1)
Isfahan University of Medical Sciences (IR), Tabriz University of Medical Sciences (IR), Universal Scientific Education and Research Network (IR), Imam Reza Hospital (IR), University of Kyrenia (CY), University of California, Davis (US)
Reduced inequalities
Openalex Percentile: Top 96%
Multiple Sclerosis Research Studies
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Polymorphisms in CLOCK and ARNTL/BMAL-1 genes in multiple sclerosis: a systematic review and meta-analysis — Amirreza Naseri, Mobina Oladghaffari, et al. · European journal of medical research (2026) | TGRS Research Map | TGRS