Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis
The approaches used in this study will enhance the quality assessment of MDR-TB and can be applied to afford test manufacturers and clinical laboratories more accurate results to guide test development, selection, and regulation. Such an approach can improve confidence in MDR-TB testing, enabling physicians to guide treatment, potentially leading to better patient outcomes.
Authors
- Timothy D. McHugh (ORCID: https://orcid.org/0000-0003-4658-8594)
- Francesca Colavita (ORCID: https://orcid.org/0000-0003-0640-8667)
- Denise M. O’Sullivan (ORCID: https://orcid.org/0000-0001-8915-7984)
- Daniel Mapamba (ORCID: https://orcid.org/0000-0001-5642-488X)
- Richard Odame Phillips (ORCID: https://orcid.org/0000-0001-8992-0222)
- Belinda Dagg
- Jim F. Huggett (ORCID: https://orcid.org/0000-0002-0945-1911)
- Rejoice Agyeiwaa Arthur
- Antonella Vulcano (ORCID: https://orcid.org/0000-0002-0023-9658)
- Bariki Mtafya (ORCID: https://orcid.org/0000-0003-3772-8671)
- Manca Žolnir-Dovč
- Gerwyn M. Jones (ORCID: https://orcid.org/0000-0003-3693-4844)
- Sven O. Friedrich
- Augustynowicz-Kopec Ewa
- Mei Mei Ho
- Daniela Maria Cirillo
- Dorothy Yeboah-Manu
- Prince Asare
Institutions
- National Tuberculosis Institute (IN)
- Vita-Salute San Raffaele University (IT)
- Environment Agency (GB)
- University of Surrey (GB)
- Mbeya University of Science and Technology (TZ)
- Task Applied Science (ZA)
- Noguchi Memorial Institute for Medical Research (GH)
- Center for Prevention and Treatment of Infections (US)
- University Clinic of Pulmonary and Allergic Diseases Golnik (SI)
- National Center for Tuberculosis and Lung Disease (GE)
- Kumasi Centre for Collaborative Research in Tropical Medicine (GH)
- Industrial Measurement Systems (United States) (US)
- University College London (GB)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1093/clinchem/hvaf178
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00