Association between cardiovascular risk and ADAM10 in cognitively healthy older adults

No evidence of a robust association between ADAM10 levels and CVRF was found. The lack of a significant association may be attributed to the insufficient number of participants classified as having high CVR. Larger samples are needed to enable more detailed analyses with optimal group stratification. We speculate that the inclusion of participants with higher levels of formal education may have contributed to this non-significant result, given the association between higher education and preventive health care.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_104801
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between cardiovascular risk and ADAM10 in cognitively healthy older adults

Cecília Patrícia Popolin, M Cominetti, M. Grigoli, A.A.G.F. Ramos et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Association between cardiovascular risk and ADAM10 in cognitively healthy older adults

Cecília Patrícia Popolin, M Cominetti, M. Grigoli, A.A.G.F. Ramos, Vanessa Alexandre da Silva, Stefany Oliveira, Lucas Nogueira de Carvalho Pelegrini, Pedro Henrique Moreira Victoriano
article en

Abstract

No evidence of a robust association between ADAM10 levels and CVRF was found. The lack of a significant association may be attributed to the insufficient number of participants classified as having high CVR. Larger samples are needed to enable more detailed analyses with optimal group stratification. We speculate that the inclusion of participants with higher levels of formal education may have contributed to this non-significant result, given the association between higher education and preventive health care.

Alzheimer s & DementiaVol. 21(S2)
Universidade Federal de São Carlos (BR), Universidade Federal de São Paulo (BR)
Openalex Percentile: Top 29%
Dementia and Cognitive Impairment Research
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