Risk of opioid overdose during buprenorphine treatment for opioid use disorder in the fentanyl era

Buprenorphine remains effective for overdose prevention in the fentanyl era among patients who remain in treatment. There was no evidence that higher doses were associated with greater overdose risk.

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Publication Details

Journal
Addictive Behaviors
Published
2026-01-06
DOI
https://doi.org/10.1016/j.addbeh.2026.108603
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk of opioid overdose during buprenorphine treatment for opioid use disorder in the fentanyl era

Marzan A. Khan, Rachel Gaither, Benjamin D. Hallowell, Laura C. Chambers et al.
Addictive Behaviors
Opioid Use Disorder Treatment
article

Risk of opioid overdose during buprenorphine treatment for opioid use disorder in the fentanyl era

Marzan A. Khan, Rachel Gaither, Benjamin D. Hallowell, Laura C. Chambers, Rachel Wightman, Andrew Zullo, Justin Berk, McClaren Rodriguez, Macy Daly, Francesca L. Beaudoin
article en

Abstract

Buprenorphine remains effective for overdose prevention in the fentanyl era among patients who remain in treatment. There was no evidence that higher doses were associated with greater overdose risk.

Addictive BehaviorsVol. 175
Rhode Island Department of Health (US), Providence College (US), Brown University (US), Rhode Island Department of Behavioral Healthcare, Developmental Disabilities and Hospitals (US)
Good health and well-being
Openalex Percentile: Top 96%
Opioid Use Disorder Treatment
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