In utero exposure to medications and congenital eye anomalies

This study provides new data on in utero exposure to medications and congenital eye anomalies that can be severely debilitating. This is a descriptive study, with all the inherent limitations of the pharmacovigilance databases which are used for signal detection. This descriptive study does not allow us to conclude that there is a causal link between exposure to a given medication during pregnancy and congenital eye anomalies and is a basis for future studies using different data sources and/or other methods.

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Publication Details

Journal
BMJ Open Ophthalmology
Published
2026-01-01
DOI
https://doi.org/10.1136/bmjophth-2024-002049
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

In utero exposure to medications and congenital eye anomalies

Christine Damase‐Michel, Marianne Lepetit, Isabelle M. E. Lacroix, Erika-Alejandra Cifuentes et al.
BMJ Open Ophthalmology
Pharmacovigilance and Adverse Drug Reactions
article

In utero exposure to medications and congenital eye anomalies

Christine Damase‐Michel, Marianne Lepetit, Isabelle M. E. Lacroix, Erika-Alejandra Cifuentes, R Mairesse, Charlotte Dubucs
article en

Abstract

This study provides new data on in utero exposure to medications and congenital eye anomalies that can be severely debilitating. This is a descriptive study, with all the inherent limitations of the pharmacovigilance databases which are used for signal detection. This descriptive study does not allow us to conclude that there is a causal link between exposure to a given medication during pregnancy and congenital eye anomalies and is a basis for future studies using different data sources and/or other methods.

BMJ Open OphthalmologyVol. 11(1)
Inserm (FR), Université Fédérale de Toulouse Midi-Pyrénées (FR), Centre Hospitalier Universitaire de Toulouse (FR), Centre de Recherches en Cancérologie de Toulouse (FR), Life Medical Control (France) (FR)
Openalex Percentile: Top 96%
Pharmacovigilance and Adverse Drug Reactions
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