A case of Wunderlich syndrome in a postliver transplant patient

Wunderlich syndrome involves spontaneous renal hemorrhage into the subcapsular and perirenal spaces, often presenting with acute flank pain, a palpable mass, and shock. While commonly associated with native kidney tumors, it can also occur in transplant recipients, including rare cases in postliver transplant patients. We report the case of a 67-year-old man with a history of liver transplantation who developed spontaneous hemorrhage of the right kidney. Emergency surgery revealed a large retroperitoneal hematoma and a Grade IV renal injury. The patient recovered well after prompt surgical intervention. This case highlights the importance of considering Wunderlich syndrome in differential diagnoses for patients with acute abdominal symptoms and renal hemorrhage, regardless of transplant history. Early diagnosis and tailored management are key to preventing severe complications.

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Publication Details

Journal
Radiology Case Reports
Published
2026-01-07
DOI
https://doi.org/10.1016/j.radcr.2025.11.031
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
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article

A case of Wunderlich syndrome in a postliver transplant patient

Luis Osvaldo Suárez Carreón, José María Zepeda Torres, Iván Chávez Orozco, Carolina Topete Rodríguez et al.
Radiology Case Reports
Tuberous Sclerosis Complex Research
article

A case of Wunderlich syndrome in a postliver transplant patient

Luis Osvaldo Suárez Carreón, José María Zepeda Torres, Iván Chávez Orozco, Carolina Topete Rodríguez, José Martínez Chávez
article en

Abstract

Wunderlich syndrome involves spontaneous renal hemorrhage into the subcapsular and perirenal spaces, often presenting with acute flank pain, a palpable mass, and shock. While commonly associated with native kidney tumors, it can also occur in transplant recipients, including rare cases in postliver transplant patients. We report the case of a 67-year-old man with a history of liver transplantation who developed spontaneous hemorrhage of the right kidney. Emergency surgery revealed a large retroperitoneal hematoma and a Grade IV renal injury. The patient recovered well after prompt surgical intervention. This case highlights the importance of considering Wunderlich syndrome in differential diagnoses for patients with acute abdominal symptoms and renal hemorrhage, regardless of transplant history. Early diagnosis and tailored management are key to preventing severe complications.

Radiology Case ReportsVol. 21(3)
Universidad de Guadalajara (MX), Hospital General De Zona (MX), Centro Médico ABC (MX)
Good health and well-being
Openalex Percentile: Top 96%
Tuberous Sclerosis Complex Research
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A case of Wunderlich syndrome in a postliver transplant patient — Luis Osvaldo Suárez Carreón, José María Zepeda Torres, et al. · Radiology Case Reports (2026) | TGRS Research Map | TGRS