Clinical proteomics in cardiovascular medicine: Current capabilities, limitations, and future directions
Beyond risk prediction, proteomics offers opportunities to elucidate disease mechanisms and enable drug repurposing. To realize the clinical potential of plasma proteomics, absolute or reliably recalibratable relative quantification will be required to guide patient care. Ultimately, the clinical value of proteomics will be determined by the quality rather than the quantity of protein measurements.
Authors
- Manuel Mayr (ORCID: https://orcid.org/0000-0002-0597-829X)
- Bhawana Singh (ORCID: https://orcid.org/0000-0002-5834-8320)
- Oleg A. Karpov (ORCID: https://orcid.org/0000-0002-1130-0098)
Institutions
- Lung Institute (US)
- Imperial College London (GB)
Publication Details
- Journal
- Atherosclerosis
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1016/j.atherosclerosis.2026.120637
- Citations
- 1
- Primary Topic
- Advanced Proteomics Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 16.26
Funders
- British Heart Foundation
- Österreichische Forschungsförderungsgesellschaft
- Bundesministerium für Verkehr, Innovation und Technologie