Enantiodivergent intermolecular hydroamination of acyclic 1,3-dienes using aniline nucleophiles

Pd-catalyzed enantioselective intermolecular hydroamination of acyclic 1,3-dienes can proceed with aniline nucleophiles, featuring enantiodivergence via modulation of non-chiral acid additives.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2026-01-01
DOI
https://doi.org/10.1039/d5qo01645b
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
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article

Enantiodivergent intermolecular hydroamination of acyclic 1,3-dienes using aniline nucleophiles

Tianlei REN, Huan Cong
Organic Chemistry Frontiers
Catalytic C–H Functionalization Methods
article

Enantiodivergent intermolecular hydroamination of acyclic 1,3-dienes using aniline nucleophiles

Tianlei REN, Huan Cong
article en

Abstract

Pd-catalyzed enantioselective intermolecular hydroamination of acyclic 1,3-dienes can proceed with aniline nucleophiles, featuring enantiodivergence via modulation of non-chiral acid additives.

Organic Chemistry FrontiersVol. 13(5)
Technical Institute of Physics and Chemistry (CN), University of Hong Kong (HK)
Openalex Percentile: Top 96%
Catalytic C–H Functionalization Methods
DOISourceOpenAlex
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