A Novel Topical Agent for the Management of Hyperpigmentation, Including Melasma and Age Spots

ND-ZnO-containing skin preparations offer a well-tolerated and effective alternative to conventional treatments for melasma and age spots. Their multi-action approach, which combines UV protection, reactive oxygen species (ROS) scavenging, and enhanced delivery of actives, supports both prevention and repair of pigmentation. These findings suggest ND-ZnO formulations may serve as a safer and more compliant option for long-term hyperpigmentation management. &nbsp.