P05 Engagement and retention of participants enrolled in mySkin, a remote monitoring tool for psoriasis

Abstract Introduction and aims Longitudinal remote monitoring enables real-time tracking of patient outcomes, with potential to personalize care and improve data collection in clinical trials. In psoriasis, self-taken photographs can complement patient-reported outcomes by providing objective information. As remote monitoring may not be equally suitable for all patients, it is crucial to understand factors influencing engagement. We sought to characterize the demographic and clinical factors associated with engagement and retention with a remote monitoring platform in mySkin, a longitudinal UK cohort study of adults with clinician-confirmed psoriasis. Methods Participants were recruited via routine care, related studies, patient organizations and social media, and self-enrolled via an online platform (https://myskin.org/). Participants completed a baseline survey on demographics and clinical characteristics, followed by 3-monthly surveys for 12 months. After each survey, they were invited to submit three optional self-taken photographs. Logistic regression identified factors associated with agreement to submit photographs, and logistic mixed models evaluated factors associated with retention. Results Among 810 participants, 90.7% were of White ethnicity, 62.5% were female, and the mean age was 51 years (SD 14.1). Engagement with photograph submission was low; while 52.7% agreed to submit photographs, only 41.2% of those who agreed submitted. Participants with moderate-to-severe psoriasis were more likely to agree to submit photographs than those with clear/nearly clear skin [odds ratio (OR) 2.66, 95% confidence interval (CI) 1.81–3.94]. Retention rates at 3, 6, 9 and 12 months were 65.9%, 58.7%, 56.5% and 55.3%, respectively. Better retention was associated with older age (OR 1.09, 95% CI 1.06–1.11), unemployment (OR 1.76, 95% CI 1.04–2.98) and mental health comorbidity (OR 2.21, 95% CI 1.32–3.69). Increased psoriasis severity was associated with poorer retention (OR 0.25, 95% CI 0.16–0.39). Conclusions Engagement and retention in remote monitoring for psoriasis varied across patient groups. Tailored strategies are needed to support sustained participation before implementation in trials and clinical practice.