Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis
Active small molecules demonstrate generally positive yet heterogeneous preventive efficacy against SCM in animal models, with polyphenolic compounds in particular showing notable potential. Variability across molecular categories, sepsis models and measured outcomes highlights the need for standardised methodologies in future studies.
Authors
- Tao Gong (ORCID: https://orcid.org/0000-0001-8668-2185)
- Nai Zhang (ORCID: https://orcid.org/0000-0003-0716-7623)
- Ying Zheng (ORCID: https://orcid.org/0000-0002-1906-9660)
- Lu Tao (ORCID: https://orcid.org/0000-0003-4920-2570)
- Yujuan Liu
- H Y Li
- Longhai Wang
- Chuang Yang
- Guiying Ye
- Chi Che
- Gen Ouyang
- Peng Zeng
- Neng Wang
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Integrated Chinese Medicine (China) (HK)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fphar.2025.1665372
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00