Open Tibial Fractures Part 2: A Narrative Review of Definitive Treatment and Potential Applicability to the Southern African Context

The purpose of this study was to conduct a review of contemporary definitive treatment options, potential complications and clinical outcomes for open tibial shaft fractures and while assessing their relevance and applicability within South African context. Treatment options available in high-income countries may not be accessible in low-resource settings, requiring adaptations to the treatment approach based on local conditions. Only one African country has attempted to establish principal guidelines for the treatment of open tibial fractures through a consensus-based approach. These guidelines cover primary assessment, antibiotics, initial stabilization, referral criteria, debridement and irrigation, documentation, wound closure, soft-tissue management, amputation, and definitive internal fixation. Unfortunately, definitive fracture management recommendations for African low-resource countries are not yet available. There is a lack of data regarding the treatment of open tibial fractures in low-resource countries, particularly in regional and rural areas. Existing guidelines address antibiotic prophylaxis and treatment, debridement and lavage, initial surgical fixation, wound closure (both primary and definitive), soft-tissue management (including flap coverage), and bone fragment retention, all adapted to local resource availability. However, guidelines for definitive treatment remain unavailable. Treatment options recommended by high-income countries are largely unsuitable, and Southern African nations should focus on developing guidelines tailored to their available resources.

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Publication Details

Journal
Orthopedic Research and Reviews
Published
2026-01-01
DOI
https://doi.org/10.2147/orr.s553515
Primary Topic
Bone fractures and treatments
Type
article
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article

Open Tibial Fractures Part 2: A Narrative Review of Definitive Treatment and Potential Applicability to the Southern African Context

Maketo Molepo, Kevin Tetsworth, Erik Hohmann, Maritz Laubscher
Orthopedic Research and Reviews
Bone fractures and treatments
article

Open Tibial Fractures Part 2: A Narrative Review of Definitive Treatment and Potential Applicability to the Southern African Context

Maketo Molepo, Kevin Tetsworth, Erik Hohmann, Maritz Laubscher
article en

Abstract

The purpose of this study was to conduct a review of contemporary definitive treatment options, potential complications and clinical outcomes for open tibial shaft fractures and while assessing their relevance and applicability within South African context. Treatment options available in high-income countries may not be accessible in low-resource settings, requiring adaptations to the treatment approach based on local conditions. Only one African country has attempted to establish principal guidelines for the treatment of open tibial fractures through a consensus-based approach. These guidelines cover primary assessment, antibiotics, initial stabilization, referral criteria, debridement and irrigation, documentation, wound closure, soft-tissue management, amputation, and definitive internal fixation. Unfortunately, definitive fracture management recommendations for African low-resource countries are not yet available. There is a lack of data regarding the treatment of open tibial fractures in low-resource countries, particularly in regional and rural areas. Existing guidelines address antibiotic prophylaxis and treatment, debridement and lavage, initial surgical fixation, wound closure (both primary and definitive), soft-tissue management (including flap coverage), and bone fragment retention, all adapted to local resource availability. However, guidelines for definitive treatment remain unavailable. Treatment options recommended by high-income countries are largely unsuitable, and Southern African nations should focus on developing guidelines tailored to their available resources.

Orthopedic Research and ReviewsVol. Volume 18
University of Cape Town (ZA), Royal Brisbane and Women's Hospital (AU), Groote Schuur Hospital (ZA), University of Pretoria (ZA)
Openalex Percentile: Top 96%
Bone fractures and treatments
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Open Tibial Fractures Part 2: A Narrative Review of Definitive Treatment and Potential Applicability to the Southern African Context — Maketo Molepo, Kevin Tetsworth, et al. · Orthopedic Research and Reviews (2026) | TGRS Research Map | TGRS