Phase 1 dose-escalation study of IBI324, a VEGF-A/Ang-2 bispecific antibody, for the treatment of diabetic macular oedema

Authors

Qinghuai Liu (ORCID: https://orcid.org/0000-0003-0351-136X)
Shujie Lu
Mengqi Wu (ORCID: https://orcid.org/0000-0001-9403-1745)
Junjie Deng
Liming Tao (ORCID: https://orcid.org/0000-0002-6333-4118)
Zilin Wang (ORCID: https://orcid.org/0009-0003-6062-3015)
Junran Sun (ORCID: https://orcid.org/0000-0003-3678-2780)
K. Liu
Xiaorong Li
Xiaodong Sun
Li Li
Lei Qian

Institutions

Shanghai Jiao Tong University (CN)
Anhui Medical University (CN)
Zhejiang Provincial People's Hospital (CN)
Shanghai First People's Hospital (CN)
Tianjin Medical University Eye Hospital (CN)
Suzhou Electrical Apparatus Science Academy (CN)
Second Affiliated Hospital of Anhui Medical University (CN)
Jiangsu Province Hospital (CN)
Tianjin Medical University (CN)

Publication Details

Journal: BMJ Open Ophthalmology
Published: 2026-01-01
DOI: https://doi.org/10.1136/bmjophth-2024-002035
Primary Topic: Retinal Diseases and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Innovent Biologics

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article

Phase 1 dose-escalation study of IBI324, a VEGF-A/Ang-2 bispecific antibody, for the treatment of diabetic macular oedema

Qinghuai Liu, Shujie Lu, Mengqi Wu, Junjie Deng et al.

Jan 1, 2026

BMJ Open Ophthalmology

Retinal Diseases and Treatments

article

Phase 1 dose-escalation study of IBI324, a VEGF-A/Ang-2 bispecific antibody, for the treatment of diabetic macular oedema

Qinghuai Liu, Shujie Lu, Mengqi Wu, Junjie Deng, Liming Tao, Zilin Wang, Junran Sun, K. Liu, Xiaorong Li, Xiaodong Sun, Li Li, Lei Qian

January 1, 2026article en

Abstract

No abstract available for this paper.

BMJ Open OphthalmologyVol. 11(1)

Shanghai Jiao Tong University (CN), Anhui Medical University (CN), Zhejiang Provincial People's Hospital (CN), Shanghai First People's Hospital (CN), Tianjin Medical University Eye Hospital (CN), Suzhou Electrical Apparatus Science Academy (CN), Second Affiliated Hospital of Anhui Medical University (CN), Jiangsu Province Hospital (CN), Tianjin Medical University (CN)

Innovent Biologics

Good health and well-being

Openalex Percentile: Top 95%

Retinal Diseases and Treatments

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Phase 1 dose-escalation study of IBI324, a VEGF-A/Ang-2 bispecific antibody, for the treatment of diabetic macular oedema — Qinghuai Liu, Shujie Lu, et al. · BMJ Open Ophthalmology (2026) | TGRS Research Map | TGRS