Aberrant Complement Activation Is a Prominent Feature of Chronic Inflammatory Demyelinating Polyneuropathy

These findings highlight the critical involvement of aberrant complement activation in the pathophysiology of CIDP and provide a rationale for further investigation into targeted complement inhibition as a therapeutic approach.

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Publication Details

Journal
Neurology Neuroimmunology & Neuroinflammation
Published
2026-01-07
DOI
https://doi.org/10.1212/nxi.0000000000200542
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Aberrant Complement Activation Is a Prominent Feature of Chronic Inflammatory Demyelinating Polyneuropathy

Jan D. Lünemann, Frauke Stascheit, Andreas Meisel, Katrin Hahn et al.
Neurology Neuroimmunology & Neuroinflammation
Peripheral Neuropathies and Disorders
article

Aberrant Complement Activation Is a Prominent Feature of Chronic Inflammatory Demyelinating Polyneuropathy

Jan D. Lünemann, Frauke Stascheit, Andreas Meisel, Katrin Hahn, Helena F Pernice, Kerstin Stein, Hannah Preßler
article en

Abstract

These findings highlight the critical involvement of aberrant complement activation in the pathophysiology of CIDP and provide a rationale for further investigation into targeted complement inhibition as a therapeutic approach.

Neurology Neuroimmunology & NeuroinflammationVol. 13(2)
German Center for Neurodegenerative Diseases (DE), Humboldt-Universität zu Berlin (DE), University Hospital Münster (DE)
Good health and well-being
Openalex Percentile: Top 95%
Peripheral Neuropathies and Disorders
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