Primary Cardiac Lymphoma With Exceptional Long-Term Survival

Primary cardiac lymphoma (PCL) is an uncommon extranodal lymphoma confined to the heart or pericardium at diagnosis and can mimic other cardiac disorders because of its nonspecific presentation. We report a 53-year-old man diagnosed in 2015 with diffuse large B-cell lymphoma involving the right atrium. He underwent surgical excision followed by six cycles of R-CHOP chemoimmunotherapy. Serial PET/CT and echocardiography confirmed sustained complete metabolic remission, and he remains disease-free 128 months after treatment. This case highlights the potential for prolonged survival in PCL when timely diagnosis, accurate histopathological confirmation, and appropriate therapy are provided.