Effect of exercise preconditioning on myocardial content of Sphingosine1-phosphate and its mechanism in rats after exhaustive exercise
In summary, beyond confirming S1P elevation with exercise preconditioning, our findings propose the S1P→MAPK signaling axis as a novel mechanistic pathway warranting future validation.
Authors
- Weiyuan Yang (ORCID: https://orcid.org/0000-0001-8983-3452)
- Jie Zhou (ORCID: https://orcid.org/0000-0003-3208-9073)
- Luoyuan Cao
- Xinnuan Wei
- Wenxing Jiang
Institutions
- Fujian Medical University (CN)
- Ningde Normal University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1371/journal.pone.0340313
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00