West Nile Virus–Associated Hemophagocytic Lymphohistiocytosis, Switzerland

A 62-year-old patient was hospitalized in Geneva, Switzerland, with an atypical manifestation of West Nile virus infection. Initially, he sought care for febrile diarrhea and vomiting; his condition deteriorated and hemophagocytic lymphohistiocytosis and meningoencephalitis developed. Corticosteroids improved his condition. We used high-throughput sequencing and ophthalmologic findings to diagnose West Nile virus.

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Publication Details

Journal
Emerging infectious diseases
Published
2025-12-01
DOI
https://doi.org/10.3201/eid3112.250776
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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West Nile Virus–Associated Hemophagocytic Lymphohistiocytosis, Switzerland

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West Nile Virus–Associated Hemophagocytic Lymphohistiocytosis, Switzerland

Florian Laubscher, Ariane Malclès, F. Pérez-Rodríguez, Christophe Marti, M. Schibler, Lena Groenendijk, Aude Nguyen, Benjamin Bruno, Clemente Lascano, Enrico Meduri
article en

Abstract

A 62-year-old patient was hospitalized in Geneva, Switzerland, with an atypical manifestation of West Nile virus infection. Initially, he sought care for febrile diarrhea and vomiting; his condition deteriorated and hemophagocytic lymphohistiocytosis and meningoencephalitis developed. Corticosteroids improved his condition. We used high-throughput sequencing and ophthalmologic findings to diagnose West Nile virus.

Emerging infectious diseasesVol. 31(12)
Good health and well-being
Openalex Percentile: Top 23%
Autoimmune and Inflammatory Disorders Research
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